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All of the 2641 SGs were testified in NOX2 and Nrf2 knockout GEO datasets (GSE7810, GSE100671) and total of 1030 SGs (39.0% of all SGs) were found in these two datasets (cutoff: P value < 0.05). We classified these 1030 SGs into 4 categories: 1) ROS-suppressed SGs, 2) ROS-promoted SGs, 3) ROS-uncertain SGs, and 4) ROS-independent SGs by analyzing expression changes in NOX2 and Nrf2 knockout GEO.
