Table 2.
Neural correlates of empathic accuracy from emotion labeling task. Smaller volume in bilateral inferior frontal, bilateral caudate, bilateral thalamus and left insula regions was associated with worse empathic accuracy from the emotion labeling task when controlling for diagnosis, age, sex, handedness, disease severity, cognitive functioning, scanner type and total intracranial volume. Results are shown at P < 0.005, uncorrected and cluster size >150mm3
Anatomical region | Cluster volume mm3 | x | y | z | Maximum T-score |
---|---|---|---|---|---|
Left inferior frontal triangularis gyrus | 6669 | −46 | 36 | 15 | 4.32 |
Left inferior frontal orbitofrontal cortex | a | ||||
Right inferior frontal triangularis gyrus | 4836 | 51 | 30 | −9 | 3.69 |
Right inferior frontal orbitofrontal cortex | a | ||||
Right caudate | 1370 | 12 | 12 | 12 | 3.04 |
Left middle frontal gyrus | 1357 | −33 | 38 | 34 | 4.38 |
Left caudate | 1313 | −14 | 8 | 12 | 3.22 |
Left middle temporal gyrus | 1171 | −64 | −27 | 3 | 4.00 |
Right thalamus | 1144 | 8 | −16 | 9 | 3.84 |
Left middle frontal gyrus | 702 | −26 | 9 | 54 | 3.51 |
Left posterior insula | 604 | −42 | −10 | 4 | 3.02 |
Left superior frontal gyrus | 476 | −24 | 52 | 24 | 3.35 |
Right gyrus rectus | 392 | 8 | 39 | −30 | 3.17 |
Left thalamus | 378 | −6 | −16 | 8 | 3.39 |
Left supplementary motor area | 290 | −6 | 24 | 57 | 4.00 |
Left inferior frontal triangularis gyrus | 263 | −48 | 21 | 26 | 3.35 |
Left precentral gyrus | 243 | −45 | 9 | 40 | 3.13 |
Right frontal pole | 233 | 28 | 57 | 12 | 3.01 |
Right frontal pole | 189 | 14 | 58 | 30 | 2.97 |
Right superior frontal gyrus | 169 | 26 | 3 | 60 | 3.32 |
Results considered significant at P < 0.005.
aSignifies that these regions were included in the cluster above.