Fig. 3.

Functional connectivity results for dmPFC. (A) ROI examining a peak activation seed region within dmPFC. Significance is shown through colors within the bar graphs; gray plotted bars correspond with young adult significant response intensities; red plotted bars correspond with older adult significant response intensities. (B–E) Results of dmPFC seed PLS. (B) LV1 connectivity map; (C) LV1 condition- and group-wise correlations, with 95% confidence intervals, between the dmPFC seed region and the whole-brain pattern of connectivity; (D) LV2 connectivity map; (E) LV2 condition and group correlations, with 95% confidence intervals, between the dmPFC seed region and the whole-brain pattern of connectivity. PLS analysis for young (gray bars) and older (dark red bars) adults contrasted connectivity across partner, parent or child, close friend, familiar acquaintance and self conditions. Correlations represent the relationship between brain scores and activity within the dmPFC seed for each condition. Brain scores represent the cross product of the group result image and the individual subject BOLD response for each given LV. For connectivity maps (B) and (D), warm colors (shades of orange and yellow) on connectivity maps correspond to positive brain scores, shown by the plotted bars above zero. Cool colors (shades of blue) on connectivity maps correspond to negative brain scores, shown by the plotted bars below zero. (Left) Lateral and medial views of left hemisphere. (Center) Dorsal view. (Right) Lateral and medial views of right hemisphere.