Fig. 4.

Functional connectivity results for vmPFC. (A) ROI examining a peak activation seed region within vmPFC. Significance is shown through colors within the bar graphs; gray plotted bars correspond with young adult significant response intensities, and red plotted bars correspond with older adult significant response intensities. (B–E) Results of vmPFC seed PLS. (B) LV1 connectivity map; (C) LV1 condition- and group- wise correlations, with 95% confidence intervals, between the vmPFC seed region and the whole brain pattern of connectivity; (D) LV2 connectivity map; (E) LV2 condition and group correlations, with 95% confidence intervals, between the vmPFC seed region and the whole-brain pattern of connectivity. PLS analysis for young (gray bars) and old (dark red bars) contrasted connectivity across partner, parent or child, close friend, familiar acquaintance and self conditions. Correlations represent the relationship between brain scores for each condition and activity within the vmPFC seed for each condition. Brain scores represent the cross product of the group result image and the individual subject BOLD response for each given LV. For connectivity maps (B) and (D), warm colors on connectivity maps (shades of orange and yellow) correspond to positive brain scores, shown by the plotted bars above 0. Cool colors on connectivity maps (shades of blue) correspond to negative brain scores, shown by the plotted bars below 0. (Left) Lateral and medial views of left hemisphere. (Center) Dorsal view. (Right) Lateral and medial views of right hemisphere.