TABLE 5.
Distribution of products generated by h15-LOX-1 with DHA, 7S-HDHA, and 7S-HpDHA (10 μM), as determined by LC-MS/MS
| Substrate | 11-Product | 14-Product | 17-Product |
| DHAa | 12 ± 1% | 40 ± 5% | 48 ± 4% |
| 7S-HDHA | 0 | 90 ± 6% | 10 ± 6% |
| 7S-HpDHA | 0 | 65 ± 8% | 35 ± 8% |
h15-LOX-1 shows altered positional specificity when reacting with 7S-HDHA and 7S-HpDHA. Note that the abbreviations “11-Product, etc.” in the column headings are used to simplify the complexity of the table labels.
a
These data were previously published (18)