Table 2.
Demographics of Study Participants Undergoing ACL Reconstruction With Perioperative and Postoperative Interventionsa
| Intervention and Study Author (Year) | No. of Patients (Male, Female) | No. of Participants, Experimental, Control | Age, y, Median (Range) or Mean ± SD | BMI, kg/m2 or [Weight, kg]; Experimental, Control | Total No. of Patients (% Male) | Total No. of Participants, Experimental, Control | Overall Age, y, Mean ± SD | Overall BMI, kg/m2 or [Weight, kg]; Mean ± SD |
|---|---|---|---|---|---|---|---|---|
| Perioperative femoral nerve blockb | 247 (53.8) | 120, 127 | 26.3 ± 4.2 | 82.0 ± 1.0 [25.3 ± 2.2] |
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| Abdallah1 (2016) Magnussen24 (2017) Okoroha27 (2018) Runner30 (2018) |
100 (64, 36) 30 (11, 19) 44 (27, 16) 73 (31, 42) |
48, 52 14, 16 23, 21 35, 38 |
32.4 (28.9-35.9) 22.35 ± 9.25 25.9 ± 11.05 24.65 ± 0.6 |
81.3, 79.4 [27.6, 25.1] 82.7, 74.4 [25.0, 23.3] |
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| Intraoperative tourniquet use | 196 (76.0) | 102, 94 | 28.0 ± 4.4 | 72.2 ± 2.2 | ||||
| Kokki17 (2000) Appell2 (1993) Nicholas25 (2001) Faggal11 (2015) Arciero3 (1996) |
31 (22, 9) 14 (14, 0) 48 (29, 19) 63 (54, 9) 40 (30, 10) |
13, 18 14, 0 25, 23 30, 33 20, 20 |
31 (16-48) (25-38) 32.5 25.2 24 (18-37.5) |
72, 75 Not indicated 72.3, 76.7 Not indicated Not indicated |
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| Postoperative supplement use | 125 (68.0) | 62, 63 | 28.5 ± 4.6 | 70.7 [26.5 ± 2.3] |
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| Tyler33 (2004) Laboute19 (2013) Barker6 (2009) |
60 (33, 27) 45 (32, 13) 20 (20, 0) |
30, 30 22, 23 10, 10 |
30.4 24 (18-45) 33 |
70.7 [25, 25.6] [28.9, 29.7] |
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| Postoperative blood flow restriction training | 84 (55.6) | 42, 42 | 27.3 ± 3.3 | 67.2 ± 8.0 | ||||
| Takarada31 (2000) Iverson15 (2016) Ohta26 (2003) |
16 (8, 8) 24 (14, 10) 44 (25, 19) |
8, 8 12, 12 22, 22 |
22.7 27.4 (18-42) 29 (18-52) |
58.8, 62.2 76.9, 77.6 65, 63 |
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| Median (range) values for pooled interventions |
160.5 (84-247) | 82 (42-120) | 27.7 (26.3-28.5) | 71.5 (67.2-82.0) [25.9 (21.9-33.3)] |
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aACL, anterior cruciate ligament; BMI, body mass index.
bAll nerve block studies compared patients who had femoral nerve blocks versus patients with no nerve blocks or adductor canal blocks; femoral nerve blocks are considered the experimental group for this analysis.