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Hat1-dependent acetylation of transcriptional regulators.(A) Subset of transcriptional regulators whose acetylation decreased at least 2.5-fold in Hat1−/− cells. (B) Hat1+/+ and Hat1−/− were grown in galactose and stained with antibodies recognizing unmodified p53 and p53 acetylated at lysine 381 (386 in human). Fluorescent signals were quantitated (right).
