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Statistical mixture methods addressing research questions
| Research questions | LASSO and ENET | SPCA | WQS | BKMR | BART |
|---|---|---|---|---|---|
| Chemical variable selection | X | X (PCs) | X (Weight) | X (PIP) | X (threshold) |
| Interactions | X | X | X | ||
| Cumulative impact | X | X | X | X | |
| Nonlinear dose response | X | X | X |
Abbreviations: PCs, Principal Components; PIP, Posterior Inclusion Probability
