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The Drosophila model for an autosomal dominant retinitis pigmentosa type 13. The scheme of the Prp8 protein and its domains. Alignment of the C-terminal part of the human (Q6P2Q9), Drosophila (A1Z8U0) and yeast (P33334) Prp8 orthologs indicating positions of the nine RP-associated mutations affecting the conserved amino acids (left). Individual RP mutations received a unique name according to the mutated amino acid (right).
