Figure 2.

Responders based on minimal clinically important difference of greater than or equal to a 25 m increase for 6MWD, greater than or equal to a 1-point increase for the TDI domain scores (magnitude of task, magnitude of effort, and functional impairment), and greater than or equal to a 4-point decrease for the SGRQ, activity domain. Dark blue bars represent the Zephyr Valve group and the light blue bars represent the SoC group. 6MWD = 6-minute-walk distance; SGRQ = St. George’s Respiratory Questionnaire; SoC = standard of care; TDI = Transitional Dyspnea Index.