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(A) tSNE plot showing B-progenitor acute lymphoblastic leukemia (B-ALL) subtypes based on RNA-seq gene expression profiling of 1988 cases. (B) Distribution of B-ALL subtypes within each age group. Subtypes are grouped as gross chromosomal abnormalities (aneuploidy or copy number gain), transcription factor (TF) rearrangement, other TF-driven, kinase-driven, and all others (Gu et al. 2019).
