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. 2020 Jul 1;370:m2031. doi: 10.1136/bmj.m2031

Table 2.

Association between study adults engaging in physical activities according to 2018 physical activity guidelines for Americans and all cause and cause specific mortality. Values are hazard ratios (95% confidence intervals) unless stated otherwise

Causes of death Types of physical activity
Insufficient aerobic or muscle strengthening (n=268 193) Muscle strengthening only (n=21 428) Aerobic only (n=113 851) Aerobic and muscle strengthening (n=76 384)
All causes
No of deaths: 43 798 2483 10 188 3350
 Model 1 1.00 0.82 (0.78 to 0.86) 0.62 (0.61 to 0.64) 0.48 (0.47 to 0.50)
 Model 2 1.00 0.91 (0.86 to 0.95) 0.69 (0.68 to 0.71) 0.58 (0.56 to 0.61)
 Model 3 1.00 0.89 (0.85 to 0.94) 0.71 (0.69 to 0.72) 0.60 (0.57 to 0.62)
Cardiovascular diseases
No of deaths: 10 242 539 2134 594
 Model 1 1.00 0.73 (0.66 to 0.82) 0.55 (0.52 to 0.58) 0.38 (0.34 to 0.42)
 Model 2 1.00 0.84 (0.75 to 0.94) 0.62 (0.59 to 0.66) 0.48 (0.44 to 0.53)
 Model 3 1.00 0.82 (0.74 to 0.92) 0.65 (0.62 to 0.69) 0.50 (0.46 to 0.56)
Cancer
No of deaths: 9974 593 2855 953
 Model 1 1.00 0.78 (0.71 to 0.87) 0.70 (0.67 to 0.73) 0.50 (0.46 to 0.54)
 Model 2 1.00 0.87 (0.78 to 0.96) 0.76 (0.73 to 0.80) 0.61 (0.56 to 0.65)
 Model 3 1.00 0.85 (0.77 to 0.95) 0.76 (0.73 to 0.80) 0.60 (0.56 to 0.65)
Chronic lower respiratory tract diseases
No of deaths: 2604 135 349 100
 Model 1 1.00 0.65 (0.53 to 0.80) 0.34 (0.30 to 0.39) 0.21 (0.16 to 0.26)
 Model 2 1.00 0.78 (0.63 to 0.95) 0.40 (0.36 to 0.46) 0.29 (0.23 to 0.37)
 Model 3 1.00 0.76 (0.62 to 0.93) 0.42 (0.37 to 0.47) 0.29 (0.23 to 0.37)
Accidents and injuries
No of deaths: 1586 125 525 241
 Model 1 1.00 1.00 (0.80 to 1.24) 0.74 (0.65 to 0.83) 0.59 (0.50 to 0.70)
 Model 2 1.00 1.09 (0.88 to 1.36) 0.82 (0.72 to 0.93) 0.70 (0.59 to 0.84)
 Model 3 1.00 1.08 (0.87 to 1.35) 0.82 (0.73 to 0.93) 0.71 (0.60 to 0.84)
Alzheimer’s disease
No of deaths: 1091 63 250 66
 Model 1 1.00 0.86 (0.62 to 1.18) 0.71 (0.61 to 0.84) 0.60 (0.46 to 0.79)
 Model 2 1.00 0.90 (0.65 to 1.25) 0.73 (0.62 to 0.86) 0.63 (0.47 to 0.84)
 Model 3 1.00 0.88 (0.64 to 1.23) 0.74 (0.62 to 0.87) 0.64 (0.48 to 0.86)
Diabetes mellitus
No of deaths: 1407 71 256 69
 Model 1 1.00 0.72 (0.55 to 0.95) 0.44 (0.37 to 0.51) 0.26 (0.19 to 0.34)
 Model 2 1.00 0.94 (0.71 to 1.24) 0.57 (0.48 to 0.67) 0.41 (0.31 to 0.54)
 Model 3 1.00 0.96 (0.73 to 1.27) 0.63 (0.53 to 0.74) 0.47 (0.36 to 0.62)
Influenza and pneumonia
No of deaths: 890 47 151 47
 Model 1 1.00 0.77 (0.55 to 1.10) 0.47 (0.38 to 0.58) 0.36 (0.26 to 0.50)
 Model 2 1.00 0.89 (0.63 to 1.25) 0.54 (0.43 to 0.67) 0.45 (0.32 to 0.63)
 Model 3 1.00 0.87 (0.62 to 1.24) 0.55 (0.44 to 0.68) 0.46 (0.32 to 0.64)
Nephritis, nephrotic syndrome, or nephrosis
No of deaths: 895 44 142 48
 Model 1 1.00 0.60 (0.42 to 0.86) 0.38 (0.32 to 0.47) 0.36 (0.25 to 0.52)
 Model 2 1.00 0.72 (0.51 to 1.03) 0.46 (0.37 to 0.55) 0.49 (0.34 to 0.71)
 Model 3 1.00 0.71 (0.50 to 1.01) 0.48 (0.40 to 0.59) 0.52 (0.36 to 0.76)

Model 1: Adjusted for sex, age, and race/ethnicity.

Model 2: Model 1+education, marital status, body mass index, smoking status, and alcohol intake.

Model 3: Model 2+chronic conditions.