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Anti-IgG inhibited PANDAS serum activation of CaMKII in a human neuronal cell line. Diluted sera (1:100) from two subjects diagnosed with PANDAS were incubated in triplicate with no beads, anti-IgG-coated beads, or BSA-coated beads and analyzed for CaMKII activation. Sera from one normal subject was also analyzed for CaMKII activation. Mann-Whitney non-parametric U test performed. ns, not significant.
