Table 2.

Sample size estimation

Outcome measure	Variance estimate	SEM	Initial sample size estimate
VO2peak (mL/kg/min)	1.69	1.0	29
Non-paretic limb knee extension strength (Nm)	72.3	10.6	11
Paretic limb knee extension strength (Nm)	43.6	12.4	5
Non-paretic limb knee flexion strength (Nm)	17.6	7.4	5
Paretic limb knee flexion strength (Nm)	16.8	10.1	3

The non-inferiority limit is the SEM. The sample size is the number of participants required per group.

SEM, SE of measurement.