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. 2020 Jul 2;82(3):251–258. doi: 10.1007/s12262-020-02466-7

Table 4.

Adjuvant radiotherapy guidelines for breast cancer during COVID-19 pandemic [31]

Suggestion no. Action Conditions
1 Omit radiotherapy Age ≥ 65 years (younger with comorbidities) + invasive breast cancer < 3 cm with clear margins + grade 1/2 + ER-positive and HER2-negative + node-negative + planned for endocrine therapy
2 Deliver radiotherapy in 5 fractions. 26 Gy in 5 daily fractions over 1 week or 28–30 Gy in once weekly fractions over 5 weeks [33] For all patients requiring radiotherapy to the whole or partial breast or chest wall
3 Omit boost radiotherapy to reduce fractions or hypofractionation Except in patients < 40 years age and those with a high risk of local recurrence
4 Omit nodal radiotherapy Postmenopausal women with T1, grade 1–2, ER-positive, HER2-negative tumour with 1–2 macro metastases requiring whole breast radiotherapy following BCS and sentinel node biopsy [34]