Table 3.
Impairment-based | Task-specific | Crossover (p-values) |
Initial groups (p-values) |
|||||
---|---|---|---|---|---|---|---|---|
BSL | POST | BSL | POST | time | time X group |
time | time X group |
|
Primary variables | ||||||||
FS (m/s) | 0.70±0.36 | 0.71±0.33 | 0.64±0.32 | 0.78±0.41 | <0.01* | 0.01* | 0.02* | 0.06 |
treadmill speed (m/s) | 0.81±0.41 | 0.82±0.43 | 0.76±0.43 | 0.96±0.48 | <0.01* | <0.01* | <0.01* | <0.01* |
Secondary clinical variables | ||||||||
SSS (m/s) | 0.53±0.28 | 0.53±0.25 | 0.51±0.26 | 0.58±0.30 | 0.10 | 0.12 | 0.10 | 0.21 |
6MWT (m) | 192±97 | 195±94 | 191±110 | 239±123 | <0.01* | <0.01* | <0.01* | 0.02* |
BBS (a.u.) | 32±12 | 33±11 | 32±14 | 35±14 | 0.03* | 0.39 | 0.14 | 0.33 |
LEMS (a.u.) | 43±6.8 | 42±10 | 42±8.0 | 41±11 | 0.53 | 0.49 | 0.49 | 0.57 |
5XSTS (s) | 17±5.1 | 14±4.5 | 16±8.3 | 15±4.7 | 0.29 | 0.64 | 0.91 | 0.44 |
stepping power (W) | 103±43 | 134±48 | 110±45 | 110±43 | 0.10 | 0.04* | 0.04* | 0.99 |
Secondary subjective variables | ||||||||
ABC (a.u.) | 55±21 | 57±21 | 48±22 | 58±23 | 0.02* | 0.01* | 0.01* | 0.03* |
PROMIS (a.u.) | 38±12 | 40±12 | 36±12 | 40±14 | 0.06 | 0.24 | 0.15 | 0.68 |
Secondary metabolic variables | ||||||||
VO2peak-treadmill (ml/kg/min) |
17±7.8 | 18±9.4 | 17±5.2 | 19±8.2 | 0.04* | 0.59 | 0.08 | 0.49 |
VO2peak-stepping (ml/kg/min) |
15±5.2 | 16±7.3 | 14±5.0 | 14±5.1 | 0.71 | 0.58 | 0.41 | 0.87 |