Table 1:
Effect of Treatment of Diet-induced Obese or Type 2 Diabetic Rats with Mito-Q on Body Weight, Blood Glucose, Serum Thiobarbituric Acid Reactive Substances and Liver Lipid Hydroperoxides
| Determination | Control | Obese | Obese + Mito-Q | Diabetic | Diabetic + Mito-Q |
|---|---|---|---|---|---|
| (9) | (8) | (9) | (9) | (9) | |
| Start weight (g) | 327 ± 2 | 323 ± 4 | 320 ± 7 | 329 ± 3 | 325 ± 3 |
| Final weight (g) | 468 ± 7 | 536 ± 13a | 551 ± 13a | 469 ± 22b | 416 ± 12b |
| Blood glucose (mg/dl) | 142 ± 7 | 167 ± 9 | 141 ± 2 | 384 ± 38a,b | 440 ± 31a,b |
| Thiobarbituric acid reactive substances (μg/ml) | 0.9 ± 0.09 | 1.04 ± 0.07 | 0.97 ± 0.07 | 1.24 ± 0.08 | 1.12 ± 0.13 |
| Lipid Hydroperoxides (nmol/g liver) | 21.7 ± 3.1 | 57.8 ± 7.8a | 42.4 ± 5.8 | 62.5 ± 3.5a | 45.4 ± 3.5a |
Data are presented as the mean ± S.E.M.
a
P < 0.05 compared to control rats;
b
P < 0.05 compared to obese rats;
c
P < 0.05 compared to diabetic rats.
Parentheses indicate the number of experimental animals.