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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: J Mol Endocrinol. 2020 Jul;65(1):T35–T48. doi: 10.1530/JME-19-0274

Figure 1. Post-translational modifications to steroid receptors.

Figure 1.

Multiple posttranslational modification sites are present in the N-terminal domain (NTD) of GR, PR, ER, and AR. PR and AR also have a serine phosphorylation site in the hinge (H) region. The annotated pro-directed sites are known to be modified by MAPKs and/or CDKs and alter SR transcriptional activity and co-factor binding. DNA-binding and ligand-binding domains are also indicated.