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Treatment with exosomes significantly reduces hippocampal neuronal cell loss after TBI. NeuN staining was performed for detection of mature neurons at day 35 after TBI in the CA3 region and dentate gyrus (DG). Representative images show NeuN+ cells in the dose response (A, B) and window response (D, E) studies. Scale bars = 100 μm. Quantitative data shown in bar graphs (C, F) represent mean ± SD. N = 8/group.
