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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Oral Biosci. 2020 Feb 17;62(2):123–130. doi: 10.1016/j.job.2020.02.002

Table 1.

Summary of the possible effect of different factors on osteoclastogenesis

Factor Promote
Osteoclastogenesis
(+)		 Inhibit
Osteoclastogenesis
(−)
miRNA-218 [67] ☑
miRNA-34a [68] ☑
miRNA-124 [69] ☑
miRNA-31 [70] ☑
miRNA-21 [71] ☑
miRNA-125a [71] ☑
IL-22 [76] ☑
⬆ M1/M2 ratio [81] ☑
M1 activation / addition to OC precursors [86] ☑
M2 activation [84] ☑
Memory B cells [88] ☑