Table 2.
Average IOP, ICP, and TLP (Mean ± SD in mmHg) for the Waking (6:00–18:00) and Sleeping (18:00–6:00) Periods Across all Days by NHP
| IOP | ICP | TLP | ||||
|---|---|---|---|---|---|---|
| NHP | Awake | Sleep | Awake | Sleep | Awake | Sleep |
| 150069 | 12.9 ± 0.6 | 13.6 ± 0.5* | 2.4 ± 0.6 | 6.4 ± 0.6† | 10.5 ± 0.9 | 7.2 ± 0.3† |
| 12.38 | 15.5 ± 0.4 | 15.4 ± 0.6 | 3.4 ± 1.9 | 8.9 ± 1.2† | 12.0 ± 1.9 | 6.5 ± 0.9† |
| 150110 | 15.9 ± 0.6 | 17.8 ± 0.8† | 5.3 ± 0.6 | 10.2 ± 1.0† | 10.5 ± 1.0 | 7.6 ± 0.3† |
| 150143 | 16.8 ± 1.2 | 16.7 ± 1.0 | 9.0 ± 1.9 | 12.9 ± 1.3† | 7.8 ± 2.3 | 3.8 ± 1.3† |
†
P < 0.01
*
P < 0.05 indicate significant change between wake and sleep. Note that ICP and TLP values are uncalibrated in NHP 150143 so absolute pressures are not valid, although relative diurnal differences in pressure are accurate.