Table 1.

Demographics and Clinical Characteristics of MIS-C Patients with Gastrointestinal Involvement

Case series	MIS-C cases, n	Age (median)/Gender, n	Incomplete KD, n (%)	GI involvements, n (%)	GI symptoms/signs, n (%)	Findings of GI system examination
Riphagen et al (2020)	8	8 y; male: 5	8 (100)	7 (88)	Diarrhea: 7 (88); vomiting: 4 (50); abdominal pain: 6 (75)	Not described in detail
Toubiana et al (2020)	21	7.9 y; male: 9	10 (48)	21 (100)	Abdominal pain with vomiting and diarrhea: 20 (95); acute surgical abdomen: 2 (10)	Abdominal ultrasound: peritoneal effusions in 4, 1 had abdominal surgery for suspected appendicitis with a final diagnosis of aseptic peritonitis
Belhadjer et al (2020)	35	10 y; male: 18	35 (100)	29 (83)	Abdominal pain, vomiting, or diarrhea present in 80	Exploratory laparoscopy in 2 cases due to suspected appendicitis, with a confirmed diagnosis of mesenteric lymphadenitis
Licciardi et al (2020)	2	9.5 y, male: 2	0	2 (100)	Abdominal pain and diarrhea: 2 (100), vomiting: 1 (50)	Abdominal ultrasound: both showed mesentery lymphadenitis or enlarged mesenteric lymph nodes
Waltuch et al (2020)	4	10 y, male: 3	3 (75)	4 (100)	Abdominal pain: 4 (100), diarrhea:	Abdominal ultrasound: mild ascites and inflammatory gallbladder in 1; abdominal CT: suspected appendicitis in 1
Dallan et al (2020)	2	10 y, male: 2	2 (100)	2 (100)	Abdominal pain: 2 (100); peritoneal signs: 2 (100); vomiting: 1 (50)	Abdominal CT: mesenteric lymphadenitis in 1

CT, computed tomography; GI, gastrointestinal; KD, Kawasaki disease; MIS-C, multisystem inflammation syndrome in children.