Table 1.

Details of Trial interventions.

Intervention	Basti group	Nasya group
	Karma Basti	Rechana nasya
Place of administration	The Basti was prepared (individually for each patient) and administered in P.G Department of Panchakarma by the Post graduated scholars.	The Nasya karma was administered in P.G Department of Panchakarma by the Post graduated scholars.
Dosage regimen and quantitative description	Karma Basti was given for 30 days. i.e. 1 Anuvasana Basti (dose −120 mL) in the beginning and 5 at the end with 12 Asthapana (dose ~ 960 mL) and 12 Anuvasana Basti on alternate days was administered for 30 consecutive days.	Rechana Nasya on alternate days was given in the dose of 8 drops (0.5 mL) per nostril for total 28 days.
Drugs	Asthapana Basti - Musta (Cyperus rotundus Linn.), Kushtha, (Saussurea costus (Falc.)Lipsch), Haridra (Curcuma longa Linn.), Daruharidra, (Berberis aristata DC.), Vacha (Acorus calamus Linn.), Ativisha (Aconitum heterophylum wall.), Katukarohini (Picrorhizakurroa Royle ex. Benth), Chitraka (Plumbago zeylanica Linn.), Chirbilva (Holopteleaintegrifolia Planch), Madhu (Pure raw honey), Saindhava (pure rock salt), Sarshapa taila (oil of Brassica campestris Linn.), Gomutra (fresh cow's urine), Yavakshara (Hordeum vulgare Linn.), Yavani (Trachispermum ammi Linn.), Madanaphala (Randia dumetorum Retz.), Bilva (Aegle marmelos Linn.), Satavari (Asparagusracemosus Wild.), Pippali (Piper longum Linn.) Anuvasana Basti–Triphaladi Taila	Triphaladi Taila - Til Taila (oil of Sesamum orientale Linn), Haritaki (Terminalia chebula Retz.), Amalki (Phyllanthus emblica Linn.), Vibhitaki (Terminalia bellirica (Gaertn) Roxb.), Ativisha (Aconitum heterophylum wall.), Nishotha (Operculina turpethum Linn.), Chitraka (Plumbago zeylanica Linn., Vaasa (Adhatoda vasica Ness (Syn.)), Nimba (Azadiracta indica A. Juss), Aragvadha (Cassia fistula Linn.), Saptaparna (Alstonia scholaris R. Br), Haridra (Curcuma longa Linn.), Daruharidra (Berberisaristata DC.), Guduchi (Tinospora cordifolia (Willd.)), Indrayana (Citrulluscolocynthis Linn.), Pippali (Piper longum Linn.), Kushtha (Saussurea costus (Falc.) Lipsch)
Method of preparation of Basti	Nirhu Basti - Yavakuta (coarse powder) of Lekhana Basti Kwath Dravya (100 g) and was boiled in 1600 ml of water, reduced to 400 mL and filtered. Honey (240 g) and powdered Saindhava (10 g) was mixed well by triturating in Khalva (mortar). Followed by addition of Sarshapa Taila (mustard oil) (120 mL), then Putiyavanyadi Kalka (80 g), then Kwath (400 mL) then Gomutra (120 mL) and Yavakshara (10 g) was added and mixed thoroughly. This mixture was made lukewarm by indirect heating by keeping the vessel containing the homogenous mixture of Basti Dravya in hot water before administration of Basti. Anuvasana Basti – Saindhava (4 g) and paste of Shatahwa (Anethum sowa Kurz.) (4 g) was mixed well by triturating in Khalva in 120 mL of Triphaladi Taila and resulting composition was filtered and indirectly heated over water bath and filled in Basti Yantra for administration.
Characteristics of the Basti dravya (Qualitative Testing)	The Basti Dravya was checked qualitatively by taking on the palm of hand. A homogenous uniform solution that neither run quickly over nor stick to palm and leaves no oil traces on the hand was considered well prepared.
Purva karma	Asthapana Basti – The Basti was given before meals both Sarvanga (whole body) Abhyanga (Ayurvedic massage) and Swedana (sudation) was administered as preparatory measure. Anuvasana Basti – The patient was subjected to Abhyanga and Swedana followed by intake of meals somewhat 1/4th less than the routine diet.	Nasya was given before the meals both Abhyanga and Swedana of head and neck region was done as preparatory measure.
Pradhana karma	The patient is made to lie in left lateral posture with right leg semiflexed and bend towards the surface. Basti netra smeared with oil is gently inserted in the anal opening in parallel direction to vertebral column. The Basti putaka is squeezed with a constant pressure to introduce Basti Dravya into the anus. A small amount of liquid is retained in the Putaka and the Basti Netra is gently removed from the anus.	Triphaladi Taila was instilled in each nostrils in the dose of 8 drops (0.5 ml) followed by Dhumapana and Ksharaambu Gandusha.
Paschat karma	Asthapana Basti - After Basti Pratyagamana patient was asked to take hot water bath and to take diet containing pulse soup in lesser quantity than the routine and advised him to avoid the Loud speaking, Excessive vehicle travelling, Excessive walking, Excessive sitting, Ajirna Bhojana (Indigestion), Unwholesome diet, Day napping and Sexual indulgence. Anuvasana Basti – After Basti administration patient was asked to maintain lying position for atleast an hour and follow restriction of Basti Karma.	After Nasya Karma patient was asked to take normal diet after 48 min and advised to avoid the Pariharya Visaya (avoidable things) as also described in Basti karma