Table 2.
Chau et al. [25] | Takahari et al. [26] | Lee et al. [27] | Kim et al. [28] | Koo et al. [29] | Fanotto et al. [31] | Fuchs et al. [41] | |
---|---|---|---|---|---|---|---|
Host status | |||||||
ECOG PS | ● | ● | ● | ● | ● | ● | ● |
Tumor status | |||||||
No gastrectomy | ● | ● | ● | ● | |||
Peritoneal metastasis | ● | ● | ● | ● | ● | ||
Bone metastasis | ● | ● | ● | ||||
Liver metastasis | ● | ||||||
Lung metastasis | ● | ||||||
Number of metastatic sites | ● | ● | |||||
First-line TTP/PFS | ● | ● | |||||
Laboratory test values | |||||||
Increased ALP | ● | ● | ● | ● | ● | ||
Increased AST | ● | ● | |||||
Decreased albumin | ● | ● | ● | ||||
Elevated total bilirubin | ● | ● | |||||
Increased LDH | ● | ● | |||||
NLR | ● |
ECOG PS: Eastern Cooperative Oncology Group performance status; TTP: time to progression; PFS: progression-free survival; ALP: alkaline phosphatase; AST: aspartate transaminase; LDH: lactate dehydrogenase; NLR: neutrophil-to-lymphocyte ratio. References [30] and [40] are reports on second-line treatment