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. 2020 Jul 1;10:10757. doi: 10.1038/s41598-020-67431-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Survival of patients with HER2 positive metastatic breast cancer by physical activity level, data not adjusted (N = 144). It shows overall survival of women with HER2 positive metastatic breast cancer according to the level of physical activity. After adjustment with a Cox regression model on age at metastatic diagnosis, BMI, tumor type, education, smoker/non-smoker status, stage IV at diagnosis, PS ECOG, number of metastatic localizations, adjuvant chemotherapy and imputations on missing data, both vigorous and moderate physical activity were associated with significantly improved overall survival compared to light physical activity level only in the HER2 positive subgroup.