Table 5.
Association between the presence of the sialidase A gene and results from fluorescence in situ hybridisation (FISH) with non-optimal vaginal microbiota (Nugent score 4–10) (N = 191).
| N | Non-optimal microbiota Pos (%) |
Odds ratio (95% CI) |
p-value |
Adjusted odds ratio (95% CI)a |
p-valueb | |
|---|---|---|---|---|---|---|
| Sialidase A gene | ||||||
| Absent | 60 | 15 (25%) | 1 | <0.001 | 1 | 0.134 |
| Present | 131 | 88 (67%) | 6.14 (3.15–12.55) | 2.29 (0.77–6.65) | ||
| Fluorescence in situ hybridisation (FISH) for Gardnerella vaginalis and Atopobium vaginae | ||||||
| Non-adherent | 85 | 8 (9%) | 1 | <0.001 | 1 | <0.001 |
| Adherent (biofilm) | 106 | 95 (90%) | 83.12 (33.74–232.60) | 67.00 (26.72–190.53) | ||
a
Variables were adjusted by the other variables in the model.
b
P-values obtained with likelihood ratio tests.