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. 2020 Jun 25;14:612. doi: 10.3389/fnins.2020.00612

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Copyright © 2020 Tai, Zheng, Zhai, Cai, Xu, Yang, Jiao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ALA suppresses the 6-OHDA-induced excessive iron accumulation in the SN of rats and PC12 cells. (A) Iron-staining cells in the SN of rats. (B) Corresponding numbers of iron-staining cells in the SN of rats. (C) The total iron content in the SN of rats was detected by using a tissue iron assay kit. (D) The total iron content of PC12 cells was detected by using a tissue iron assay kit. Data were expressed as the means ± SD analyzed by one-way ANOVA (n = 3). Statistical significance: *P < 0.01 vs. sham group or control; ^#P < 0.01 vs. PD group or 6-OHDA.