Table 1.
Pediatric NMOSD population | German | French | Brazilian | UK | US network | Multinational | Catalonia (Spain) | US |
---|---|---|---|---|---|---|---|---|
n = 7 (15) | n = 12 (16) | n = 29 (17) | n = 20 (18) | n = 38 (6) | n = 12 NMO, 33 limited forms (19) | n = 5 (20) | n = 16 (21) | |
Mean age at onset | 9.6 (5–14) | 14.5 (4–17.9) | 13 (5–17) | 10.5 (2.9–16.8) | 10.2 ± 4.7 | 9 (0.75–17) | n/a | 12 (1–15) |
Female/Male ratio | 2.5:1 | 3:1 | 2.6–1 | 9:1 | <11 years = 1.5:1 >11 years = 3.25:1 |
1:1 | 1.5:1 | 3:1 |
AQP4-IgG positive | 2/7 | 8/12 | 22/27 | 12/20 | 24/37 | 5/45 | 2/5 | 70% |
MOG-IgG positive | – | – | – | – | – | 25/45 | 1/5 | – |
Race | White = 6/7 Arabian = 1/7 |
White = 8/12 Asian = 2/12 Black = 1/12 American Indian 1/12 |
Caucasian = 41% Mixed = 52% African = 7% |
n/a | White = 37% African American = 37% Asian = 11% |
Caucasian = 91% Non-Caucasian = 9% |
n/a | White = 31% |
Ethnicity | Non-Hispanic/non-Latino = 37% Hispanic/ Latino = 13% |