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. 2020 Jun 25;14:613. doi: 10.3389/fnins.2020.00613

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Copyright © 2020 Liu, Qiao, Wang, Wu, Su, Wang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of MiR-224-5p Improved the Morphology and Increased the Number of Primary Cortical Neurons After OGD. (A) The images of transfection of Cy3 in neurons. (B) The transfection efficiency of neurons. (C) The mimic of miR-224-5p could promote the expression of miR-224-5p, and the inhibitor of miR-224-5p could inhibit the expression of miR-224-5p (^∗∗P < 0.01). (D) The images of primary cortical neurons in the control group, OGD group, mimic-NC group, anti-NC group, miR-224-5p group, and anti-miR-224-5p group. (E) Inhibition of miR-224-5p increased the number of neurons after OGD injury (^∗∗P < 0.01).