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. 2020 Jun 25;14:613. doi: 10.3389/fnins.2020.00613

FIGURE 7.

FIGURE 7

Inhibition of MiR-224-5p Reduced the Apoptosis of Neurons Through NR4A1. (A) The apoptosis of neurons (red) was observed in the control group, OGD group, anti-miR-224-5p group, anti-miR-224-5p + si-NC group, anti-miR-224-5p + si-NR4A1 group, and anti-NC + si-NR4A1 group. Nuclei were visualized by DAPI (blue). (B) The apoptotic ratio of neurons was quantified. The apoptotic ratio of neurons significantly increased in the anti-miR-224-5p + si-NR4A1 group compared with the anti-miR-224-5p + si-NC group (∗∗P < 0.01). (C) The viability of neurons was quantified by MTT. The viability of neurons was markedly decreased in the anti-miR-224-5p + si-NR4A1 group compared with the anti-miR-224-5p + si-NC group (∗∗P < 0.01).