Table 3.
Kyoto Encyclopedia of Genes and Genomes Enrichment Analysis following differential gene expression analysis of high HERV-K expressing Hepatoblastoma vs low HERVK expressing Hepatoblastoma.
| Functional Category | Genes in list | Total genes | Enrichment False Discovery Rate (Adjusted p-value) |
|---|---|---|---|
| Amoebiasis | 14 | 96 | 0.000793149 |
| Complement and coagulation cascades | 12 | 78 | 0.001119036 |
| Fatty acid degradation | 8 | 44 | 0.005062775 |
| Legionellosis | 9 | 55 | 0.005062775 |
| Peroxisome | 10 | 82 | 0.012590092 |
| Focal adhesion | 17 | 199 | 0.012590092 |
| Human papillomavirus infection | 24 | 330 | 0.012590092 |
| PI3K-Akt signaling pathway | 24 | 353 | 0.020654396 |
| Rheumatoid arthritis | 10 | 89 | 0.020654396 |
| ECM-receptor interaction | 9 | 82 | 0.034941883 |
| AGE-RAGE signaling pathway in diabetic complications | 10 | 100 | 0.034941883 |
| Epithelial cell signaling in Helicobacter pylori infection | 8 | 68 | 0.034941883 |
| Salmonella infection | 9 | 85 | 0.036101621 |
| Regulation of actin cytoskeleton | 16 | 214 | 0.036577774 |
| Tryptophan metabolism | 6 | 42 | 0.038157306 |
| Oocyte meiosis | 11 | 124 | 0.041198024 |
| IL-17 signaling pathway | 9 | 92 | 0.047460432 |
| Toxoplasmosis | 10 | 111 | 0.04997533 |