Table 4.

Expression of SPM receptor genes in gingival tissues.

SPM receptor gene	Relative expression in healthy (H)	Relative expression in Periodontitis before non-surgical therapy (P)	Relative expression in periodontitis after non-surgical therapy (A)	Relative fold change between H and P	Relative fold change between H and A	Relative fold change between A and P
ALX (FPR2)	1.936	2.698	1.988	0.762	0.052	0.711
BLT1 (LTB4R)	1.046	0.545	0.618	−0.502	−0.428	−0.074
ChemR23 (ERV1)	2.157	1.642	1.79	−0.516	−0.367	−0.148
GPR18 (DRV2)	1.868	1.98	1.295	0.112	−0.572	0.684
GPR32 (DRV1)	0.563	0.431	0.735	−0.131	0.172	−0.304
GPR37	0.687	0.627	0.624	−0.059	−0.062	0.003
LGR6	0.919	0.808	0.740	−0.112	−0.179	0.067

Numbers highlighted in bold indicate statistically significant difference (FDR adjusted p-value < 0.05). Expression levels are present in log₂ mean of relative gene expression (2^−ΔΔCT). The relative fold change is present in the log₂ value between the two groups with the first group as the reference group.