TABLE 2.
Intersections of significant hits from multiple platforms.
| Comparison | DNAm and RNA | DNAm and Protein | RNA and Protein | DNAm and RNA and Protein |
| all_families | PTPRN2(↑ – ↓) | – | – | – |
| wo_fam_1 | – | – | – | – |
| wo_fam_2 | – | – | – | – |
| wo_fam_3 | HLA-DQB1(↓ – ↓), IL5RA(↓ – ↑), KIF19 (↑ – ↓) |
– | – | – |
| wo_fam_4 | – | – | – | – |
| wo_fam_5 | – | – | ICAM1(↑ – ↓), APOL1(↑ – ↑), CD14(↑ – ↑) |
– |
| wo_fam_6 | – | – | JCHAIN(↑ – ↑) | – |
For each comparison including all families, and each possible 5 × 5 comparison between CALD and non-CALD, the significant hits (p-value < 0.05 before multiple testing correction) from DNA methylation (DNAm), RNA-sequencing (RNA), and protein LCMS (Protein) were intersected. (↑ means up-regulated/higher for CALD, ↓ means lower in CALD). Intersections with no hits are marked by ‘–.’