Table 2. Summary of diagnostic performance of NEWS to predict adverse outcome.

	5 day outcome	30 day outcome
	NEWS ≥5	NEWS ≥7	NEWS ≥5	NEWS ≥7
	Death (95% CI)	Death or critical care admission (95% CI)	Death (95% CI)	Death or critical care admission (95% CI)	Death (95% CI)	Death or critical care admission (95% CI)	Death (95% CI)	Death or critical care admission (95% CI)
NEWS recorded by GP
Sensitivity	49%(33-65)	38%(31-47)	21%(10-36)	25%(18-33)	37%(29-46)	37%(30-45)	23%(16-31)	24%(18-32)
Specificity	83%(81-84)	84%(82-85)	93%(91-94)	94%(92-95)	83%(82-85)	84%(82-85)	93%(92-94)	94%(92-95)
Positive predictive value	5%(3-8)	15%(12-19)	5%(2-10)	22%(16-29)	12%(9-16)	15%(12-19)	17%(12-24)	23%(17-30)
Negative predictive value	99%(98-99)	95%(94-96)	98%(98-99)	94%(93-95)	96%(95-96)	94%(93-95)	95%(94-96)	94%(93-95)
Positive likelihood ratio	2.8(2.1–3.9)	2.3(1.9–2.9)	2.8(1.5–5.1)	3.9(2.8–5.3)	2.2(1.8–2.8)	2.3(1.8–2.8)	3.4(2.4–4.8)	3.8(2.8–5.2)
Negative likelihood ratio	0.6(0.5–0.8)	0.7(0.7–0.8)	0.9(0.7–1.0)	0.8(0.7–0.9)	0.8(0.7–0.9)	0.8(0.7–0.9)	0.8(0.8–0.9)	0.8(0.7–0.9)
NEWS recorded by ambulance
Sensitivity	62%(46-77)	53%(45-62)	42%(27-59)	32%(24-40)	54%(45-62)	53%(45-61)	24%(18-30)	31%(24-39)
Specificity	67%(64-70)	69%(66-72)	85%(83-87)	86%(84-88)	69%(66-72)	69%(66-72)	86%(84-88)	86%(84-88)
Positive predictive value	7%(4-10)	21%(17-25)	9%(6-15)	26%(20-33)	19%(15-23)	21%(17-26)	24%(18-30)	26%(20-33)
Negative predictive value	98%(97-99)	91%(88-93)	98%(96-98)	89%(87%–91%)	92%(90-94)	90%(88-92)	86%(84-88)	89%(87-91)
Positive likelihood ratio	1.9(1.5–2.5)	1.7(1.4–2.1)	2.8(1.9–4.1)	2.3(1.7–3.1)	1.7(1.4–2.1)	1.7(1.5–2.1)	1.7(1.3–2.3)	2.2(1.7–3.0)
Negative likelihood ratio	0.6(0.4–0.8)	0.7(0.6–0.8)	0.7(0.5–0.9)	0.8(0.7–0.9)	0.7(0.6–0.8)	0.7(0.6–0.8)	0.9(0.8–1.0)	0.8(0.7-.0.9)

NEWS = national early warning scores.