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. 2020 May;12(5):2039–2048. doi: 10.21037/jtd-19-4206

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2020 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The expression pattern of DACT2 in the myocardial tissues of patients with valvular heart disease. (A,B) Immunohistochemistry evaluating DACT2 expression in the SR (A) and AF (B) groups. (C,D) Masson’s trichrome staining indicating fibrosis severity in the SR (C) and AF (D) groups. The sections indicated in A and C were obtained from the same SR patient, and the sections indicated in B and D were obtained from the same AF patient. Scale bars: 100 µm. (E) Fibrosis ratios of the AF and SR groups. (F) Fibrosis ratios of the weak and strong DACT2 expression groups. *, P≤0.05; **, P≤0.01. SR, sinus rhythm; AF, atrial fibrillation.