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. 2020 May 4;21:278–289. doi: 10.1016/j.omtn.2020.04.018

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Overexpression of miR-4500 Represses the Expression of RRM2 to Inhibit Breast Cancer Cell Proliferation

(A) The cell proliferation detected by the EdU proliferation assay (400×). (B) Quantitative analysis for EdU-positive breast cancer cells detected by the EdU proliferation assay. (C) The protein protein expressions of RRM2 and cell proliferation-related factors Ki67 and PCNA detected by Western blot. (D) Comparison of relative protein expressions of RRM2 and cell proliferation-related factors Ki67 and PCNA in each group.. The data comparisons were analyzed by one-way ANOVA, and the experiment was repeated three times independently.