Table 2.
Baseline characteristics of the participants (N = 238).
| Characteristic | UA quartiles (μmol/L) | P value | |||
|---|---|---|---|---|---|
| Q1 (103-256) | Q2 (262-322) | Q3 (323-384) | Q4 (387-573) | ||
| No. of participants | 58 | 59 | 57 | 64 | |
| Age (years, median, Q1-Q3) | 67.50 (56.25-73.75) | 64.00 (55.00-74.00) | 65.00 (57.00-71.00) | 62.00 (53.00-69.00) | 0.182 |
| Systolic BP (mmHg, mean ± sd) | 160.71 ± 25.80 | 155.22 ± 22.96 | 155.47 ± 20.47 | 161.81 ± 23.60 | 0.271 |
| Diastolic BP (mmHg, median, Q1-Q3) | 86.00 (78.25-98.75) | 85.00 (78.00-95.50) | 84.00 (78.00-94.00) | 88.00 (79.00-100.25) | 0.266 |
| Total cholesterol (mmol/L, median, Q1-Q3) | 4.50 (3.87-5.00) | 4.64 (4.21-5.37) | 4.48 (4.20-4.93) | 4.80 (4.08-5.40) | 0.521 |
| Triglyceride (mmol/L, median, Q1-Q3) | 1.39 (0.98-1.99) | 1.44 (1.11-1.97) | 1.80 (1.21-2.45) | 1.67 (1.36-2.76) | 0.009 |
| HDL cholesterol (mmol/L, median, Q1-Q3) | 1.12 (0.93-1.31) | 1.09 (0.94-1.28) | 1.02 (0.91-1.15) | 1.03 (0.95-1.17) | 0.107 |
| LDL cholesterol (mmol/L, median, Q1-Q3) | 2.51 (2.09-3.20) | 2.60 (2.25-3.40) | 2.64 (2.39-2.98) | 2.70 (2.25-3.21) | 0.772 |
| Creatinine (μmol/L, median, Q1-Q3) | 66.00 (54.00-75.00) | 69.00 (60.00-85.00) | 76.00 (67.00-88.00) | 87.50 (70.00-104.00) | <0.001 |
| Urea nitrogen (μmol/L, median, Q1-Q3) | 5.42 (4.56-6.46) | 5.45 (4.59-6.32) | 5.51 (4.41-6.45) | 5.33 (4.39-6.37) | 0.944 |
| Homocysteine (μmol/L, median, Q1-Q3) | 11.64 (8.90-14.28) | 12.00 (9.87-14.61) | 12.91 (10.40-15.30) | 13.05 (10.87-16.91) | 0.015 |
| Sex (n, %) | <0.001 | ||||
| Male | 27 (46.55%) | 38 (64.41%) | 39 (68.42%) | 53 (82.81%) | |
| Female | 31 (53.45%) | 21 (35.59%) | 18 (31.58%) | 11 (17.19%) | |
| Hypertension (n, %) | 0.337 | ||||
| No | 25 (43.10%) | 24 (40.68%) | 16 (28.07%) | 26 (40.62%) | |
| Yes | 33 (56.90%) | 35 (59.32%) | 41 (71.93%) | 38 (59.38%) | |
| Diabetes (n, %) | 0.994 | ||||
| No | 49 (84.48%) | 50 (84.75%) | 48 (84.21%) | 55 (85.94%) | |
| Yes | 9 (15.52%) | 9 (15.25%) | 9 (15.79%) | 9 (14.06%) | |
| Coronary artery disease (n, %) | 0.096 | ||||
| No | 46 (79.31%) | 54 (91.53%) | 53 (92.98%) | 57 (89.06%) | |
| Yes | 12 (20.69%) | 5 (8.47%) | 4 (7.02%) | 7 (10.94%) | |
| Smoking (n, %) | 0.013 | ||||
| No | 45 (77.59%) | 44 (74.58%) | 35 (61.40%) | 34 (53.12%) | |
| Yes | 13 (22.41%) | 15 (25.42%) | 22 (38.60%) | 30 (46.88%) | |
| Drinking (n, %) | 0.111 | ||||
| No | 53 (91.38%) | 44 (74.58%) | 46 (80.70%) | 50 (78.12%) | |
| Yes | 5 (8.62%) | 15 (25.42%) | 11 (19.30%) | 14 (21.88%) | |
| NIHSS | <0.001 | ||||
| Minor stroke (NIHSS ≤ 5) | 28 (48.28%) | 40 (67.80%) | 50 (87.72%) | 55 (85.94%) | |
| Moderate to severe stroke (NIHSS > 5) | 30 (51.72%) | 19 (32.20%) | 7 (12.28%) | 9 (14.06%) | |
Note: the continuous variable of nonnormal distribution is calculated by Kruskal-Wallis H test. BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein; UA: uric acid; NIHSS: National Institutes of Health Stroke Scale.