Table 3.
Multivariable linear regression analysis of hepatic features in WD patients with and without cirrhosis
| Beta | Standard error | P-value | |
|---|---|---|---|
| Liver function indices | |||
| ALT (U/L) | - | - | - |
| AST (U/L) | - | - | - |
| Albumin (g/L) | - | - | - |
| PT (s) | 0.908 | 0.314 | 0.004 |
| INR | 0.089 | 0.032 | 0.040 |
| Total cholesterol (mmol/L) | -0.400 | 0.199 | 0.047 |
| Triglyceride (mmol/L) | -0.299 | 0.145 | 0.041 |
| Bilirubin (μmol/L) | - | - | - |
| Portal hypertension | |||
| Portal vein diameter (mm) | 1.330 | 0.320 | <0.001 |
| Hematocytopenia | |||
| WBC (109/L) | -0.709 | 0.286 | 0.014 |
| RBC (1012/L) | -0.253 | 0.127 | 0.048 |
| Platelet (109/L) | -71.016 | 13.615 | <0.001 |
Adjusted for age, sex, body mass index, disease duration, hypertension, diabetes, alcoholism and smoking. ALT, alanine transaminase; AST, aspartate transaminase; INR, international normalized ration; PT, prothrombin time; RBC, red blood cell; WBC, white blood cell; WD, Wilson disease.