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. 2020 Jul 1;3(7):e2013880. doi: 10.1001/jamanetworkopen.2020.13880

Table 2. Associations Between Current, Incident, and Long-term Use of NSAIDs in the Main Propensity-Matched Study Cohort.

Exposure Risk among NSAID use cohort, % (95% CI) Risk among NSAID nonuse cohort, % (95% CI) Risk difference, % (95% CI) Risk ratio (95% CI)
Intensive care unit admission
Current use 20.0 (16.6 to 23.4) 16.0 (12.8 to 19.1) 4.0 (–0.6 to 8.7) 1.25 (0.96 to 1.63)
Incident use 25.0 (13.7 to 36.3) 17.9 (7.8 to 27.9) 7.1 (–8.0 to 22.3) 1.40 (0.68 to 2.88)
Long-term use 28.2 (20.8 to 35.6) 14.8 (9.0 to 20.6) 13.4 (4.0 to 22.8) 1.90 (1.19 to 3.06)
30-d mortality
Current use 7.1 (4.9 to 9.3) 6.9 (4.7 to 9.1) 0.2 (–2.9 to 3.3) 1.03 (0.66 to 1.60)
Incident use 7.1 (0.4 to 13.9) 7.1 (0.4 to 13.9) 0.0 (–9.5 to 9.5) 1.00 (0.26 to 3.80)
Long-term use 7.0 (2.8 to 11.3) 4.9 (1.4 to 8.5) 2.1 (–3.4 to 7.6) 1.43 (0.56 to 3.65)

Abbreviation: NSAID, nonsteroidal anti-inflammatory drug.