Table 1. Fleischner society recommendations for subsolid nodules (2017) from Migliore (1).

Solitary pure ground-glass nodules

Nodule size ≤5 mm

No CT follow up required

Nodule size >5 mm

Follow up CT at 3 months, then annual CT for at least 3 years

Solitary part-solid nodules

Initial follow-up CT at 3 months

If persistent and solid component <5 mm

Annual CT for at least 3 years

If persistent and solid component ≥5 mm

Biopsy or surgical resection

Multiple subsolid nodules

Pure ground glass nodules ≤5 mm

CT at 2 and 4 years

Pure ground glass nodules >5 mm, without a dominant lesion(s)

Initial follow-up CT at 3 months then annual CT for at least 3 years

Dominant nodule(s) with part-solid or solid component

Initial follow-up CT at 3 months

If persistent, biopsy or surgical resection (especially if has >5 mm solid component)

CT, computed tomography.