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. 2020 Jun 12;10(16):7436–7447. doi: 10.7150/thno.46534

Figure 2.

Figure 2

Size characterization of GEVs. A. Average size of GEVs isolated via differential ultracentrifugation according to mode diameter measured by NanoSight NTA. n=15-16 per group. B. Representative 62kx cryo-EM image of a 70.96 nm FUS hyperthermia-exposed GEV isolated by differential ultracentrifugation. C. Representative 29kx cryo-EM image of several GEVs treated with FUS hyperthermia. Particle diameters in this image range from 56.27 to 79.98 nm. Statistical significance assessed by unpaired two-tailed t-test. “n.s.” = not significant.