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. 2020 May 30;10(16):7131–7149. doi: 10.7150/thno.44564

Figure 8.

Figure 8

EV-coated multi-antigenic nanovaccines-induced therapeutic protection against S. aureus BW15. (A) Skin lesion sizes were monitored over the course of infection. (means ± SD; n = 6). (B) Images of skin lesions from different groups on day 14. (C) The affected skin and major organs, including the (D) heart, (E) liver, (F) spleen, (G) lung, and (H) kidney were collected and the bacterial burdens were enumerated. Bacterial enumeration data are presented as the geometric mean ± SD (n = 6). *P < 0.05, **P < 0.01, ***P < 0.005, vs the saline group.