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. 2020 Jun 5;10(16):7335–7350. doi: 10.7150/thno.45971

Figure 2.

Figure 2

miR-139-5p inhibits CRC proliferation, migration and invasion in vitro. (A) Growth curves of CRC cells transfected with an agomir (miR-139-5p) or antagomir (anti-miR-139-5p) of miR-139-5p or their negative controls, as revealed by CCK-8 analyses. (B) Colony formation assays were performed on CRC cells transfected with miR-139-5p, anti-miR-139-5p, or corresponding negative controls. (C) Apoptosis rates and cell cycle distributions of CRC cells transfected with miR-139-5p, anti-miR-139-5p, or their negative controls. (D) Transwell migration and invasion assays were performed on CRC cells transfected with miR-139-5p, anti-miR-139-5p, or their negative controls. The results are representative results (n=3) from experiments performed in triplicate. The results are expressed as the means±SDs. **, P<0.01.