Table 2.

Univariate and multivariate analyses of factors associated with disease-free survival in CRC¹ patients

Variable	HR2	95% CI3	P value
Univariate analysis
Age (≤66.3 vs >66.3)	0.998	0.985-1.011	0.772
Sex (female vs male)	1.212	0.916-1.604	0.179
Tumor size (≤5 vs >5 cm)	0.827	0.621-1.101	0.193
Tumor differentiation (well/moderate vs poor)	0.186	0.139-0.249	<0.001
Tumor invasion (T1-T3 vs T4)	0.357	0.265-0.480	<0.001
Lymph node metastasis (absent vs present)	0.136	0.098-0.189	<0.001
Distant metastasis (absent vs present)	0.113	0.081-0.157	<0.001
AJCC4 stage (I-II vs III-Ⅳ)	0.133	0.095-0.186	<0.001
miR-139-5p expression (high vs low)	0.250	0.187-0.333	<0.001
Multivariate analysis
Tumor differentiation (well/moderate vs poor)	0.809	0.544-1.202	0.294
Tumor invasion (T1-T3 vs T4)	0.669	0.218-2.058	0.484
Lymph node metastasis (absent vs present)	0.336	0.114-0.984	0.047
Distant metastasis (absent vs present)	0.485	0.314-0.749	0.001
AJCC stage (I-II vs III-Ⅳ)	0.489	0.344-0.694	<0.001
miR-139-5p expression (high vs low)	0.415	0.300-0.576	<0.001

1. CRC: Colorectal cancer.

2. HR: Hazard ratio.

3. CI: Confidence interval.

4. AJCC: American Joint Committee on Cancer.