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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: Environ Sci Technol. 2019 Jul 10;53(15):9203–9213. doi: 10.1021/acs.est.9b02226

Table 3.

Exponentiated beta (β) coefficients are shown for the multivariate linear models of log10-transformed OPE and thyroid hormone concentrations. The model was constructed using a stepwise variable selection procedure based on Akaike information criterion optimization.

Model TNBP TNEP TCEP TCIPP TDCIPP TPHP
Hormone 10β (95% CI) p 10β (95% CI) p 10β (95% CI) p 10β (95% CI) p 10β (95% CI) p 10β (95% CI) p
fT4 (ng/dL)
Model A 1.07 (0.982,1.17) 0.116 0.954 (0.872,1.05) 0.309 1.00 (0.896,1.12) 0.976 1.01 (0.885,1.15) 0.877 0.958 (0.683,1.34) 0.801 0.926 (0.706,1.21) 0.571
Model B 0.996 (0.933,1.06) 0.909 0.969 (0.909,1.03) 0.329 1.03 (0.952,1.11) 0.458 0.897 (0.817,0.986) 0.026 1.10 (0.869,1.39) 0.418 1.21 (0.999,1.47) 0.052
Model C 1.04 (0.945,1.14) 0.422 1.00 (0.929,1.08) 0.949 0.990 (0.927,1.06) 0.763 0.806 (0.738,0.881) <0.001 1.38 (1.15,1.66) 0.001 1.27 (1.04,1.56) 0.020
TT4 (ug/dL)
Model A 1.12 (0.910,1.37) 0.283 0.954 (0.776,1.17) 0.645 1.11 (0.859,1.43) 0.422 1.12 (0.831,1.52) 0.437 1.26 (0.583,2.72) 0.550 0.809 (0.436,1.50) 0.491
Model B 1.03 (0.846,1.25) 0.784 0.994 (0.823,1.20) 0.953 1.13 (0.901,1.43) 0.277 1.03 (0.780,1.37) 0.817 1.36 (0.675,2.74) 0.381 0.974 (0.549,1.73) 0.928
Model C 1.04 (0.861,1.25) 0.678 0.891 (0.764,1.04) 0.132 1.25 (1.10,1.43) 0.001 0.853 (0.715,1.02) 0.076 1.70 (1.18,2.46) 0.006 1.22 (0.816,1.82) 0.323
TT3 (ng/dL)
Model A 1.56 (0.869,2.79) 0.133 0.725 (0.402,1.31) 0.276 1.32 (0.643,2.73) 0.437 1.98 (0.836,4.69) 0.117 2.46 (0.274,22.2) 0.411 0.429 (0.074,2.50) 0.338
Model B 1.27 (0.717,2.23) 0.407 0.804 (0.461,1.40) 0.431 1.40 (0.715,2.76) 0.315 1.60 (0.706,3.64) 0.252 2.99 (0.384,23.2) 0.287 0.682 (0.127,3.67) 0.648
Model C 0.876 (0.499,1.54) 0.636 0.784 (0.496,1.24) 0.286 2.10 (1.41,3.12) <0.001 0.961 (0.567,1.63) 0.879 2.59 (0.859,7.80) 0.089 1.72 (0.516,5.74) 0.366
Bold *:

p<0.05

Model A: no covariates

Model B: cholesterol as covariate

Model C: all covariates – cholesterol, age, breed, sampling season, years in current residence, year adopted, location, time spent outdoors, and weight