Table 2.
Baseline characteristics of subjects by quartiles of TC
| TC (mmol/l) | Q1(≤4.20) (n = 1315) |
Q2(> 4.20, ≤ 4.80) (n = 1287) |
Q3(> 4.80, ≤ 5.40) (n = 1292) |
Q4(> 5.40) (n = 1289) |
P value |
|---|---|---|---|---|---|
| Age (Years) | 38(18) | 46(22)* | 50(23)*# | 55(21)*#※ | < 0.001 |
| Male (%) | 833(63.4) | 809(62.9)* | 800(61.9)*# | 734(56.9)*#※ | < 0.001 |
| BMI (kg/m2) | 22.54 ± 2.95 | 23.12 ± 2.94* | 23.48 ± 2.95*# | 23.84 ± 3.11*#※ | < 0.001 |
| Overweight (24 ≤ BMI < 28) (%) | 340(25.9) | 418(32.5)* | 471(36.5)*# | 502(38.9)*#※ | < 0.001 |
| Obesity (BMI ≥ 28) (%) | 56(4.3) | 64(5.0)* | 77(6.0)*# | 114(8.8)*#※ | < 0.001 |
| SBP (mmHg) | 120.27 ± 16.71 | 124.36 ± 17.67* | 126.50 ± 18.83*# | 130.88 ± 19.42*#※ | < 0.001 |
| DBP (mmHg) | 72.52 ± 10.58 | 74.97 ± 11.25* | 76.33 ± 11.38*# | 78.45 ± 11.24*#※ | < 0.001 |
| TG (mmol/L) | 1.08 ± 0.76 | 1.28 ± 0.85* | 1.49 ± 0.96*# | 1.87 ± 1.27*#※ | < 0.001 |
| HDL-C (mmol/L) | 1.37 ± 0.34 | 1.32 ± 0.30* | 1.29 ± 0.29*# | 1.21 ± 0.25*#※ | < 0.001 |
| LDL-C (mmol/L) | 2.03 ± 0.38 | 2.55 ± 0.34* | 2.98 ± 0.37*# | 3.67 ± 0.67*#※ | < 0.001 |
| BUN (mmol/L) | 4.79 ± 1.07 | 4.98 ± 1.13* | 5.07 ± 1.19*# | 5.15 ± 1.13*#※ | < 0.001 |
| FPG (mmol/L) | 5.08 ± 0.65 | 5.20 ± 0.81* | 5.26 ± 0.80*# | 5.41 ± 0.99*#※ | < 0.001 |
| SCr (μmol/L) | 82.26 ± 13.48 | 82.75 ± 13.91 | 83.03 ± 13.61* | 83.13 ± 13.88*# | 0.371 |
| SUA (mg/dl) | 5.44 ± 1.28 | 5.56 ± 1.32* | 5.65 ± 1.36*# | 5.83 ± 1.39*#※ | < 0.001 |
| Hypertension (%) | 131(10.0) | 192(14.9)* | 227(17.6)*# | 299(23.1)*#※ | < 0.001 |
| Diabetes (%) | 42(3.2) | 53(4.0)* | 41(3.2)# | 62(4.8)*#※ | 0.089 |
| eGFR (ml/min/1.73m2) | 90.81 ± 15.67 | 87.60 ± 16.09* | 84.84 ± 14.35*# | 81.56 ± 13.40*#※ | < 0.001 |
| New incident CKD (%) | 27(2.1) | 54(4.2)* | 43(3.3)*# | 103(8.0)*#※ | < 0.001 |
*Compared with Q1 group, P < 0.05. #Compared with Q2 group, P < 0.05. ※Compared with Q3 group, P < 0.05