Table 4.
Baseline characteristics of subjects by quartiles of LDL
| LDL (mmol/l) | Q1(≤2.30) (n = 1321) |
Q2(> 2.30, ≤ 2.80) (n = 1292) |
Q3(> 2.80, ≤ 3.30) (n = 1280) |
Q4(> 3.30) (n = 1290) |
P value |
|---|---|---|---|---|---|
| Age (Years) | 40(19) | 46(23)* | 50(23)*# | 54(18)*#※ | < 0.001 |
| Male (%) | 745(56.4) | 781(60.4)* | 837(65.4)*# | 813(63.0)*#※ | < 0.001 |
| BMI (kg/m2) | 22.29 ± 2.93 | 23.01 ± 2.98* | 23.59 ± 2.91*# | 24.10 ± 2.98*#※ | < 0.001 |
|
Overweight (24 ≤ BMI < 28) (%) |
318(24.1) | 386(29.9)* | 487(38.0)*# | 540(41.9)*#※ | < 0.001 |
| Obesity (BMI ≥ 28) (%) | 49(3.7) | 61(4.7)* | 84(6.6)*# | 117(9.1)*#※ | < 0.001 |
| SBP (mmHg) | 121.53 ± 18.07 | 123.60 ± 17.72* | 126.75 ± 18.62*# | 130.13 ± 19.13*#※ | < 0.001 |
| DBP (mmHg) | 73.26 ± 11.35 | 74.38 ± 11.00* | 76.52 ± 11.34*# | 78.11 ± 10.95*#※ | < 0.001 |
| TC (mmol/L) | 3.91 ± 0.58 | 4.51 ± 0.45* | 5.01 ± 0.42*# | 5.92 ± 0.71*#※ | < 0.001 |
| TG (mmol/L) | 1.35 ± 1.40 | 1.35 ± 0.96 | 1.43 ± 0.80*# | 1.59 ± 0.78*#※ | < 0.001 |
| HDL-C (mmol/L) | 1.31 ± 0.34 | 1.30 ± 0.32 | 1.28 ± 0.29* | 1.29 ± 0.26* | 0.065 |
| BUN (mmol/L) | 4.81 ± 1.11 | 4.96 ± 1.14* | 5.03 ± 1.14*# | 5.20 ± 1.13*#※ | < 0.001 |
| FPG (mmol/L) | 5.12 ± 0.81 | 5.17 ± 0.73* | 5.28 ± 0.85*# | 5.38 ± 0.89*#※ | < 0.001 |
| SCr (μmol/L) | 80.73 ± 13.83 | 82.56 ± 13.73* | 83.82 ± 13.63*# | 84.11 ± 13.41*# | < 0.001 |
| SUA (mg/dl) | 5.35 ± 1.33 | 5.54 ± 1.31* | 5.69 ± 1.34*# | 5.90 ± 1.35*#※ | < 0.001 |
| Hypertension (%) | 164(12.4) | 190(14.7)* | 209(16.3)*# | 286(22.2)*#※ | < 0.001 |
| Diabetes (%) | 44(3.3) | 40(3.1) | 57(4.5)*# | 57(4.4)*# | 0.147 |
| eGFR (ml/min/1.73m2) | 90.39 ± 16.53 | 87.05 ± 15.37* | 85.29 ± 14.53*# | 82.06 ± 13.37*#※ | < 0.001 |
| New incident CKD (%) | 49(3.7) | 49(3.8) | 42(3.3)*# | 87(6.7)*#※ | < 0.001 |
*Compared with Q1 group, P < 0.05. #Compared with Q2 group, P < 0.05. ※Compared with Q3 group, P < 0.05