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circ_ANRIL targets and regulates miR-622. a Paired miR-622 seed sequence and seed recognition site in the 3ʹ-UTR of wild-type (circ_ANRIL-Wt) and (circ_ANRIL-Mut) are indicated. b Dual-luciferase reporter assay showed the putative complementary sites between miR-622 and circ_ANRIL. c, d circ_ANRIL silencing increased miR-622 expression level in OGD/R treated HBMECs. circ_ANRIL upregulation has the opposite effect. **p < 0.01. n = 3
