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. 2020 Jul 2;15:173. doi: 10.1186/s13023-020-01452-2

Table 1.

Patient characteristics

German chronic cohort
(n = 147)
US ALF cohort
(n = 28)
Age at blood sample collection (years) 35 (16–69) 26 (15–57)
Female gender 79 (54%) 20 (71%)
ALT (U/L) 36 (10–436) 36 (7–1463)
AST (U/L) 30 (8–580) 188 (43–4481)
GGT (U/L) 33 (5–471)
Bilirubin (mg/dL) 0.7 (0.3–7.8) 31.4 (4.5–67.6)
Albumin (g/L) 44 (22–53) 24 (16–28)
Urea (kU/L) 6.1 (1.0–11.9)
Sodium (mmol/L) 139 (131–149)
Creatinine (mg/dL) 0.7 (0.4–2.4) 1.2 (0.4–7.1)
WBC count (× 109/L) 5.9 (2.5–12.8) 13.4 (3.4–54.9)
INR 1.1 (0.9–2.0) 2.8 (1.7–6.5)
Phosphate (mmol/dL) 2.9 (1.0–11.7)
Serum copper (μmol/L) 4.5 (0.1–29.9) 0.3 (0.2–208.0)
Ceruloplasmin (g/L) 0.10 (0.01–0.32) 0.17 (0.04–0.45)
Urinary copper (μmol/day)†, ‡ 2.5 (0.2–27.5) 40,110.2 (661.4–9,931,842.2)

ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyltransferase, WBC white blood cell, INR international normalized ratio

Values are obtained at the same time as the blood samples used to measure soluble CD163

Data are medians (ranges) for continuous variables and total number (%) for categorical variables

n = 17 in US ALF cohort

n = 108 in German chronic cohort