Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Off-target seeding probabilities (exact seeds). The surfaces show the probability that seeding is off-target as a function of the divergence rate μ and of the number N of duplicates. The results are shown for exact seeds of size γ = 19 and for reads of size k = 50 nucleotides sequenced with an error rate p = 0.01. The divergence rate μ is defined as the probability that a given duplicate differs from the target at any given position. Note the factor 1,000 in the scale of the z-axis.
